Human Sera
Cayman Chemical PhosphatIdylcholInchIcken 50mg
A mixture of phosphatidylcholines isolated from chicken egg; the most abundant phospholipids in mammalian, plant, and yeast cells; found mainly in the outer leaflet of cell membranes and can make up approximately half of the total phospholipids; a substrate for various enzymes in cell signaling pathways
Cayman Chemical olyloyethyl phsphorylchol 50mg
Oleyloxyethyl phosphorylcholine is an inhibitor of PLA2 with an IC50 value of 6.2 µM for porcine pancreatic PLA2.{879}
Cayman Chemical 1H 1H 2H 2HPRfluorodecnsu 50mg
A polyfluoroalkyl substance; has been found as a contaminant in sea and river water
Cayman Chemical Z3Dodecenyl E2butenoAT 100mg
A female sex pheromone produced by the sweet potato weevil
Cayman Chemical S-5-FluorowIlardIIn 100mg
An agonist of GluA1 and GluA2; selectively activates GluA1 and GluA2 over GluA3 and GluA4 in voltage-clamp assays using X. laevis oocytes expressing the flip isoforms of the rat receptors (EC50s = 0.382, 0.463, 20.9, and 11.9 µM, respectively); induces evoked population spikes in isolated rat CA1 hippocampal slices in an in vitro model of seizure-like activity (EC50 = 0.03-0.08 µM)
Cayman Chemical PropacetamolhydrochLRIde 100mg
A prodrug form of acetaminophen; reduces acetic acid-induced writhing in mice and LPS-induced pyresis in rats at 200 and 600 mg/kg, respectively; induces hepatotoxicity, decreases hepatic GSH, SOD, and GPX levels, increases hepatic MDA and nitrotyrosine levels, and increases mortality in mice at 1200 mg/kg
Cayman Chemical SCH 202676hydrobromIde 50mg
A reversible inhibitor of both agonist and antagonist binding to diverse GPCRs; blocks the binding of radiolabeled ligands to human opioid, adrenergic, muscarinic, dopaminergic, adenosine, and purinergic receptors with IC50 values of 0.1 to 1.8 µM
Cayman Chemical Reagent 2R2 2mL
Reagent 2 (R2) has been tested and formulated to work exclusively with Cayman’s Total and Direct Bilirubin Colorimetric Assay Kit (Item No. 701720).
Cayman Chemical LInoleIc AcIdpRoxID free 100mg
An essential ω-6 PUFA; the most abundant PUFA in a variety of foods; dietary sources include vegetable oils, meats, nuts, seeds, and eggs; increases migration of IEC-6 rat intestinal epithelial cells in a wound healing assay at 30 μM; rats fed a linoleate-deficient diet exhibit decreased body weight and an increased ratio of eicosatrienoate to arachidonate in liver and serum phospholipids compared with rats fed a control diet, as well as mild scaling of forepaw skin
Cayman Chemical ZatebradInhydrochlorIde 50mg
Blocks If currents through HCN channels in sinoatrial node cells (IC50s = 1.83, 2.21, 1.9, and 1.88 µM, respectively for HCN1-4 in vitro); reduces heart rate from 600 to 200 beats per minute with an ED50 value of 1.8 mg/kg and induces increasing arrhythmia at concentrations >10 mg/kg when assessed through telemetric ECG recording in mice
Cayman Chemical AbIrateron Acetate 50mg
A CYP17A1 inhibitor (IC50s = 17 and 18 nM for inhibition of C17,20-lyase and 17α-hydroxylase activities, respectively); prodrug form of abiraterone; reduces plasma testosterone levels, increases plasma luteinizing hormone levels, and reduces ventral prostate, seminal vesicle, testis, and kidney weight in mice at 0.1 and 0.5 mmol/kg per day; reduces SARS-CoV-2 viral load in the culture supernatant of infected Vero E6 cells (EC90 = 8.4 μM) and is active in a plaque reduction assay (EC50 = 1.94 μM)
Cayman Chemical UmIfenovIrhydrochlorIde 50mg
A broad-spectrum antiviral agent; inhibits the replication of H5N1 influenza (IC50 = 30 UG/ml) and SARS-CoV-2 in vitro (IC50 = 3.537 µM); inhibits entry of HCV pseudoparticles in Huh7 cells (IC50 = 6 UG/ml); reduces the formation of influenza-induced lung lesions in ferrets at 45 mg/kg
Cayman Chemical MethapyrIlenhydrochLRIde 100mg
An H1 receptor antagonist (Ki = 4.5 nM) and non-genotoxic carcinogen; induces liver tumors in rats at 0.1% in the diet; decreases H3K9 and H3K56 acetylation, as well as H3K4 di- and H4K20 trimethylation, in rat liver at 40 mg/kg per day for six weeks
Cayman Chemical R3Oxocyclopentncarboxy 50mg
A synthetic intermediate useful for pharmaceutical synthesis.